Though originally intended for patients with type 2 diabetes, GLP-1 medications lead to weight loss for people with and without diabetes. In a double-blind trial of 1,961 adults with obesity or overweight but not diabetes, participants in the group using semaglutide and lifestyle intervention lost an average of 14.9 percent of their starting weight. Seventy percent of the participants in the semaglutide trial group lost at least 10 percent of their starting weight. A double-blind randomized clinical trial using tirzepatide also found strong weight loss results. In this trial, adults with obesity had average weight loss of 19.5 percent with 10 milligram (mg) doses of tirzepatide, and 20.9 percent average weight loss with 15 mg doses. While studies show that significant weight loss is likely when using GLP-1 medications, MedicGLP Calibrate has collected results to prove the efficacy of its weight loss program that includes medication plus lifestyle intervention. Since launching in 2020, Calibrate has collected results and published reports on member outcomes to prove its efficacy. In the 2023 Results Report, 2,643 member results were analyzed. In this analysis of 2,643 members, the Calibrate weight loss program led to 15 percent average weight loss. At 12 months, members had lost 15.6 percent on average. At 15 months, the average weight loss was 15.9 percent. After 24 months, the average weight loss was 16.8 percent, MedicGLP daily supplement though only 38 users participated for 24 months. In addition to weight loss, Calibrate results show improvements in some metabolic health markers. Examples of the metabolic markers tracked by Calibrate include waist circumference, cholesterol, triglycerides, hemoglobin A1C (a blood test that indicates average blood sugars for the last three months), and liver enzymes.
Science continues to prove that the old adage "you are what you eat" is profoundly true. This is because you have trillions of microorganisms living in your gut, which are directly responsible for nearly every aspect of your health. These microbes make up what’s called your "gut microbiota." They are especially influential in determining your likelihood of gaining excessive weight, becoming obese, and developing obesity-related diseases like diabetes, heart disease, and premature death. The gut microbiome (the expressed genes of your gut microbiota) plays a major role in your metabolism through energy production, storage, and expenditure. So, it’s no surprise that science has found a strong connection between gut microbiome imbalance and metabolic syndrome. Yikes! If you have the wrong mix of microbes, it could be making it tough for you to get your health on track! Did you know: Scientists can actually look at your gut microbiome composition and tell with 90% accuracy if you are obese or lean. That’s pretty impressive, isn’t it?
1. Unable to lose weight and keep it off? 2. Struggling to fight cravings? 3. Sick of starving yourself for weight loss? 4. Baffled as to why no diet seems to really work for you? Depending on the composition of your gut microbiome, your microbes can either boost your health or weigh you down (figuratively and literally). The good news is this: You have control over these little guys with every bite you eat. Diet has the power to change the landscape of your gut microbiome. So, if you’ve tried multiple diets and can’t seem to get the results you want, it’s time to look into your gut microbiome.Will You Lose Weight Naturally on an Individualized Diet? If you’ve been struggling to lose weight and keep it off - it could be your gut microbiome. While Viome doesn’t guarantee weight loss, it has been an exciting result many of our customers have reported. "Fiona’s update day 37!
We know weight loss can be tough. Find out if your weight struggles are due to a gut microbiome imbalance with Viome - and let’s tip the scales in your favor. Your gut microbes actually digest much of your food for you. When your gut microbiota help digest your food, they turn it into nutrients, neurotransmitters, vitamins, hormones, and more. Through these metabolites, the composition of your gut microbiome influences nearly every metabolic activity. It’s accurate to think of your gut microbiome as an organ that’s part immune system and part energy regulator. If your gut microbiome is imbalanced, certain bacteria end up working to protect themselves from the harsh environment and are not able to help you. In the worst case scenario, you can have microbiota adding to your health problems, making it harder for you to get healthy and lose weight. Viome’s metatranscriptomic technology has allowed us identify microbial pathways and functions, specifically those that influence weight loss or gain.